Microvenous anastomosis: The rat tail model alternative
نویسندگان
چکیده
منابع مشابه
The effect of low-molecular-weight heparin on microvenous thrombosis in a rat model.
OBJECTIVE To assess the impact of a low-molecular-weight heparin sodium, dalteparin sodium, on a thrombogenic microvenous anastomosis, using a randomized, blinded animal model. METHODS Using male Sprague-Dawley rats, 70 IU/kg of dalteparin sodium (for the treatment group) or isotonic sodium chloride solution (for the control group) were administered subcutaneously in a blinded randomized fash...
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OBJECTIVES In an effort to evaluate pharmacologic agents for optimal anticoagulant prophylaxis in patients undergoing free tissue transfer, we evaluated the efficacy of desirudin (Canyon Pharmaceuticals, Hunt Valley, MD), a recombinant hirudin that acts as a direct thrombin inhibitor, using a rat model of microvenous thrombosis. STUDY DESIGN Randomized, blinded study using an in vivo rat mode...
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OBJECTIVE To compare venous thrombosis rates among animals treated with aspirin, clopidogrel bisulfate, and ketorolac tromethamine using an anastomotic "tuck" model. DESIGN Single-blind randomized animal study. SETTING An animal laboratory at a tertiary care academic referral center. SUBJECTS Forty-two retired Lewis breeder rats divided into 3 equal groups. INTERVENTIONS Before surgical...
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ژورنال
عنوان ژورنال: Hand and Microsurgery
سال: 2020
ISSN: 2458-7834
DOI: 10.5455/handmicrosurg.110982